LIBERIA MEDICAL &
DENTAL ASSOCIATION
JOURNAL
The Liberia Medical & Dental Association Journal (LMDAJ) is owned and published by the Liberia Medical & Dental Association. All rights reserved.
Welcome to The Liberia Medical
& Dental Association Journal
The Liberia Medical & Dental Association Journal (LMDAJ) publishes contributions from medical researchers of scientific and educational interest to medical and dental practitioners and researchers as well as those in related disciplines, with special focus on medical practice and research in Africa and its peoples. The aim of this Journal is to provide a medium for international dissemination of research findings originating in Liberia, and the greater West African subregion, to promote cooperation amongst and between medical researchers in Africa and elsewhere. The Journal is published in English and French. Printed supplements are published upon arrangement with the Editor-In-Chief.
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Format of submitted articles should be submitted in the following format: Title, Authors (include institutional affiliation, Abstract (Structured), Key words, Background, Objectives, Introduction, Materials and Method, Results, Discussion and Conclusion.
Commentary..
From The Editor
The resurgence of the Liberia Medical and Dental Association Journal in 2024 marks a significant milestone in our collective effort to address the pressing health challenges in Liberia and the broader West African region. This publication aims to serve as a beacon of knowledge, providing healthcare professionals with the latest research, insights, and discussions pertinent to our region’s unique health landscape. As we celebrate this return, it is imperative to draw attention to two interconnected and increasingly prevalent health issues: diabetes and kidney disease. – Professor Philip Zochonis Ireland, Editor-in-Chief, Liberia Medical and Dental Association Journal
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Extreme Facial Dysmorphism – Is this a Rare Case of Severe Fetal Alcohol Syndrome (FAS)?
Fetal Alcohol Syndrome (FAS) is a well-documented consequence of prenatal alcohol exposure, presenting with a spectrum of physical, developmental, and neurobehavioral abnormalities. We present a rare case of severe FAS characterized by extreme facial dysmorphism in a neonate born to a mother with chronic alcohol consumption during pregnancy. The infant exhibited marked craniofacial disproportion, low-set ears, hypertelorism, and macrocephaly. The mother consumed locally brewed sugarcane liquor throughout pregnancy, contributing to the observed teratogenic effects. This case underscores the urgent need for public health interventions and education to mitigate the risks associated with alcohol use during pregnancy.
Pattern of Long Bone Fracture at John F. Kennedy Memorial Hospital (2019)
Background: The pattern of fracture, including the etiology, types, anatomical location and age distribution, may differ from and within sub-regions due to inhabitants’ occupation and living environment. We aimed to determine the pattern of long bone fractures seen through the trauma unit at the John F. Kennedy Memorial Hospital.
Methods: A retrospective study of patients with long bone fractures of the extremities at the John F. Kennedy Memorial Hospital over a period of 12 months between January 2019 to December 2019.
Results: 233 patients with long bone fractures were recruited. The resulting data was analyzed using Prism 8. Patients ages range from 4-100 years with a mean age of 38.5 years, and 18-59 years (192/233, 82.4%) being the most affected age group. There was male preponderance with male to female ratio of 2.3:1. Of the 233 fractures, 169 (72.6%) were as a result of road traffic accidents (RTA), 38 (16.4%) due to fall from heights and 26 (11.2%) from assault and pathology. Femur, tibia and tibio-fibula were the topmost three anatomical locations involved. 108 (46.4%) of all fractures were open while 125 (53.6%) were closed fractures. Eighteen had multiple associated injuries with head injury being the topmost associated injury.
Conclusion: Fractures of the lower extremities constitute the common anatomical location among the population studied. Road traffic accidents still remain one of the most prevalent etiology. Age group between 18- 59 are commonly affected. This confirms the vulnerability of the young and working population as well as poor traffic regulations in Liberia.
Indication and outcome of Simple Prostatectomy- Multicenter Review
Background: Open prostatectomy for the surgical management of benign prostate hyperplasia (BPH) is now rarely used in most developed countries except for large prostates. However, in resource limited countries, open prostatectomy remains the main mode of surgical management of benign prostate hyperplasia irrespective of the prostate size. Surgical treatment is reserved for refractory cases, as well as cases involving recurrent urinary retention, recurrent urinary tract infection, recurrent hematuria, bladder calculi or upper urinary tract involvement. The study highlights the surgical management of BPH using open simple prostatectomy with emphasis on indication and outcome.
Methods: This is a 5-year retrospective descriptive study performed at the 2 Referral Hospitals from 2018 to 2023.
Results: 60 patients were reviewed following simple prostatectomy. The age range was 55 years to 78 years with a mean age was 65.1 years. The mean preoperative hemoglobin was 11.6 g/dl. The age range was 55 years to 78 years with a mean age was 65.1 years. The mean preoperative hemoglobin was 11.6 g/dl. The perioperative transfusion rate was 27/60 (45%). BPH and Chronic urinary retention was the commonest indication for surgery which was 16/60 (26.6%) of all cases. About 45/60 (75.0%) of the procedures were performed through the transvesical approach. Systemic hypertension 31/60 (51.7%) was the commonest comorbidity. The data showed a strong correlation between patients with indwelling catheter before surgery and surgical site infection 9/13 (69.2%).
Conclusion: In the absence of endourological procedures, simple prostatectomy is broadly performed for all sizes of prostate. The postoperative morbidity is high, but the outcome is acceptable.
Risk Factors for Surgical Site Infection following Elective Inguinal Hernia Repair at Jackson F. Doe Memorial Regional Referral Hospital: Prospective study of 161 patients
Background: Surgical site infection (SSI) is a common postoperative complication that causes significant morbidity and mortality, increases antibiotic usage, prolongs hospital stay, adds cost, and decreases patients’ quality of life and has a high disease burden in developing countries.
Objectives: The purpose of this study was to assess the incidence of SSI and to identify risk factors for surgical site infection rate among clean open hernia repair.
Methods: Non-matched Prospective randomized study was conducted using pretested structured questionnaire among 161 patients undergoing elective inguinal hernia repair at Jackson F. Doe Referral Regional Hospital, Lower Nimba/ Liberia from July 2016 to February 2017.
Results: With one month follow-up, there were 19 and 7 superficial and deep surgical site infections respectively making an overall surgical site infection rate of 26(16.15%) among the study groups, with the majority (88.46%) being detected postoperatively after discharged. The rate of surgical site infection was analyzed by patient characteristics and peri-operative variables. Analysis identified two from patient characteristics and three from peri-operative variables correlating to the occurrence of SSI; Inguino-scrotal hernia (AOR=4.40, CI:1.44-13.48, p=0.009), Blood group AB (AOR=7.03, CI:1.35-36.65, p= 0.021), Povidone iodine for skin preparation (AOR=3.71, CI:1.09-12.61,p=0.035), duration of surgery >60 min(AOR=3.34, CI=1.25-8.96, p=0.017), Residents/ medical officer(AOR=4.57, CI:1.28-16.29, p= 0.019). The mean total hospital stay was also significantly longer in patients with wound infection (p=0.0001)
Conclusion: This study identified high rates of surgical site infection. This study calls that all risk factors should be regarded as potential indicators of SSI and effective and relevant preventive measures should be taken to reduce SSI and improve outcomes.
Dural Sinus Thrombosis in a 14year old girl – A Case Report
Dural sinus thrombosis is a rare but serious condition, especially in children, requiring a high level of suspicion for accurate diagnosis and timely treatment. We present the case of a 14-year-old female who initially presented with vague symptoms but later developed neurological deficits. Imaging revealed left acute mastoiditis and dural sinus thrombosis. She was successfully treated with antibiotics and anticoagulation therapy. This case underscores the importance of maintaining a high index of suspicion, utilizing imaging for accurate diagnosis, and prompt initiation of treatment in resource-limited settings.
Varicocele and Infertility in African Men – A Systematic Review
Background: Infertility is a global problem. The region with the highest rate of infertility included Central and Eastern Europe and Australia. The incidence is thought to be much higher in Sub-Saharan Africa, but the data is challenged by under-reporting. Despite most men with varicocele being fertile, it is still the most common diagnosis in infertile males.
Objective: The objective of the study is to evaluate the role of varicocele repair in improving semen parameters and achieving spontaneous pregnancy by males with infertility and clinically palpable varicocele in SSA.
Methodology: A thorough systematic literature review was conducted from 1990 to 2022 using the various academic search engines: PubMed, Google Scholar, African Journal Online and Google. The English and French Literature was searched using the medical search heading (MEsH) Varicocele and Infertility in Male appended with the following indexes: Guidelines, Sub-Saharan Africa, Senegal, Liberia, Guinea, Ghana, Nigeria, Kenya, Uganda, Tanzania and Burkina Faso.
Results: there was a significant improvement in the semen parameters after varicocelectomy in SSA men ranging from 27.7% to 100% especially those with oligospermia. The mean pregnancy rate achieved in partners of SSA men after varicocelectomy was about 38.7%.
Conclusion: Conclusions drawn from several studies have shown significant improvement in semen parameter and spontaneous pregnancy after varicocele repair in amongst couples with infertility. Males with infertility, clinically palpable varicocele and abnormal semen parameter should be offered varicocele repair.